Putting the Brakes on Inflammation
Aug. 1, 2013
A team led by a University of Arizona researcher has discovered a previously unknown mechanism that prevents the immune system from going into overdrive. That could shed light not only on how our body controls its response to pathogens but on conditions such as autoimmune diseases, allergies and chronic inflammation. The group found a protein previously believed to only play a role in blood clotting acts to tell defense cells to slow down, thereby preventing an immune reaction from spiraling out of control. Sourav Ghosh, assistant professor in the department of cellular and molecular medicine at the UA College of Medicine, and Dr. Jonathan Leighton of the Mayo Clinic will discuss the new findings.